abstract |
It is described a process for the preparation of (R) - (-) - 2-hydroxy-2- (2-chlorophenyl) acetic acid of the general formula (I), wherein the racemic 2-hydroxy-2- (2- chlorophenyl) acetic acid is resolved with a substituted amine of the general formula (II), where R21means hydroxymethyl group or carboxyl group, R2 means phenyl group, nitrophenyl group or a C1-C4 alkyl group substituted with an amino group, R3 means hydroxyl group or hydrogen atom. |