| abstract |
Described is a glucopyranozyloxybenzene derivative of formula (I) wherein R 1 is hydrogen or hydroxy (C 1-6 alkyl); R 2 represents C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkylthio, hydroxy (C 1-6 alkyl), hydroxy (C 1-6 alkoxy), hydroxy (C 1-6 alkylthio), C 1-6 alkoxy substituted A (C 1-6 alkyl) group, a C 1-6 alkoxy-substituted (C 1-6 alkoxy) group, or a C 1-6 alkoxy-substituted (C 1-6 alkylthio) group, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof which is an inhibitor of human SGLT2 and itself it is also useful for the prevention or treatment of diabetes or its complications, the use of the derivative for the manufacture of a medicament for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complication or obesity and a benzylphenyl intermediate. |