abstract |
Compounds of formula (I) wherein A is a bicyclic or tricyclic azepine derivative, the use of these compounds for the manufacture of medicaments, and pharmaceutical compositions containing the compounds are useful in the treatment of dysentery, nocturnal enuresis and nocturia. The compounds of formula (I) are vasopressin V2 receptor agonists and can therefore be used as antidiuretic and procoagulant agents, particularly in the treatment of nocturnal enuresis, nocturia, polyuria, urinary dysfunction, urinary incontinence and bleeding disorders. |