| abstract |
The bis-amino acid hydroxyethylaminosulfonamide compounds of formula (I) are effective as retroviral protease inhibitors and in particular as HIV protease inhibitors. Disclosed are retroviral protease inhibitors, more particularly selected compounds, compositions and methods for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactic prevention of retroviral infection or spread of retrovirus, and treatment of retroviral infection. |