abstract |
Described are (1R, 2S, 4R) - (-) - 2- (dimethylaminoethoxy) -2-phenyl-1,7,7-trimethylbicyclo [2.2.1] heptane, m.p. j. deramciclane, in free base or pharmaceutically acceptable acid addition salt form, containing no more than 0.2 wt. (1R, 2S, 4R) -3- (dimethylaminoethyl) -1,7,7-trimethylbicyclo [2.2.1] heptan-2-one or a pharmaceutically acceptable acid addition salt thereof, a medicament containing it, and for use in the preparation of anxiolytic drugs . (1R, 2S, 4R) -3- (Dimethylaminoethyl) -1,7,7-trimethylbicyclo [2.2.1] heptan-2-one is a by-product of the preparation of deramciclane. |