| abstract |
The enteric coated pharmaceutical composition comprises a) a tablet core comprising an acid labile drug which is 2 ', 3'-dideoxyinosine, provided that the core does not contain an alkalizing agent in an amount that will provide protection to the drug, and b) enteric a coating surrounding the tablet, the enteric coating comprising an alkalizing agent, and the enteric coating imparts protection to the core such that the core is afforded protection in an environment with a low pH of 3 or less while being able to release the drug at a pH of 4.5 or more and the composition is free of a protective backing layer between the core and the enteric coating. Also described is a process for preparing the composition. |