| abstract |
Peptide derivatives of formula (I) wherein the substituents p, q, R 1, R 2, R 3, R 4, Y, n and B have specific meanings, a process for their preparation and pharmaceutical preparations containing them. The disclosed derivatives are used as competitive inhibitors for trypsin-like proteases such as thrombin, especially for the treatment of conditions where inhibition of thrombin (e.g., thromboses) is desired, and as anticoagulants. |