Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- |
filingDate |
1995-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b4c21b27a63249323a2f135f3ed8744 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e92eff4ee2be27dc38b42530da51675d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afc451b9adf8ed4c42c27a1be8cca01e |
publicationDate |
2004-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
SK-283850-B6 |
titleOfInvention |
Actin-resistant variants of human DNase I, their preparation, use and pharmaceutical compositions containing them |
abstract |
The amino acid sequences of variants of human DNase I having reduced binding affinity to actin are shown. Also disclosed are nucleotide sequences encoding such actin-resistant variants, thereby allowing the production of these variants in amounts sufficient for clinical use. Further provided are pharmaceutical compositions and therapeutic uses of actin-resistant variants of human DNase I |
priorityDate |
1995-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |