| abstract |
The quinoxalinediones of formula (I) wherein R is a 5-membered heteroaryl containing 3 or 4 N heteroatoms attached to the quinoxalinedione ring via a C or N ring, or a 6-membered heteroaryl containing 1 to 3 N heteroatoms, which is attached to the quinoxalinedione ring via ring C, each of which optionally has a fused benzo group and each of these groups, including the fused benzo group, is optionally substituted with 1 or 2 substituents; R 1 and R 2 are each independently H, F, Cl, Br, alkyl of 1 to 4 C or haloalkyl of 1 to 4 C; and pharmaceutically acceptable salts thereof; a process and intermediates for making these quinoxalinedions; pharmaceutical compositions based on these compounds and their use. à |