| abstract |
Described are benzopyran derivatives of formula (I) wherein A is oxygen or sulfur or methylene; B and C are: a) when B is a benzofused heterocycle (a) wherein U is O, S or N, ZY is a double carbon or double bond and T is a single bond, methylene or carbonyl, C may be -CSNR7, -SO2NR7-, -CH2O; CH = CH; b) when B is phenyl (b), C may be -SO 2 NR 7 -, -CH 2 O-, -CH = CH-; D is 5-tetrazolyl or -COOR 8 wherein R 8 is hydrogen, (C 1 -C 4) -alkyl or phenylalkyl; and m and n are integers between 0 and 4. These substances have leukotriene antagonistic activity and are valuable as anti-inflammatory and anti-allergic drugs or for the treatment of cardiovascular diseases. |