http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SK-280938-B6
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 |
| filingDate | 1991-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f29be5fa643ebc1a29630b29b6bc0f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_376a1f939a6c7530eda576d7525ca758 |
| publicationDate | 2000-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SK-280938-B6 |
| titleOfInvention | METHOD OF SYNTHESIS OF (4R-CIS) -1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE AND INTERMEDIATE PRODUCTS |
| abstract | (4R-cis) -1,1-Dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate of formula (I) is synthesized by first reacting (4R-cis) with ) -1,1-Dimethylethyl-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate is treated with a compound of formula ArS (O2) X, wherein Ar is phenyl substituted with one or two substituents selected from from the group consisting of halogen and nitro and X represents halogen, in the presence of a base and a solvent, to give a compound of formula (II) wherein Ar is as defined above; and then in a second step the compound of formula (II) is treated with a compound of formula M-CN, wherein M is an alkali metal, silver or monovalent copper, in a solvent at a temperature of from 0 ° C to 100 ° C to give a compound of formula (I) ). Also described are 6-arylsulfonyloxymethyl intermediates for the preparation of a compound of formula (I) |
| priorityDate | 1990-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.