| abstract |
Disclosed are substituted pyrimidines of the general formula (I) wherein R1, R2, R3 and R4 are independently H, alkyl containing 1 to 6 carbon atoms, or perfluoroalkyl containing 1 to 6 carbon atoms; R5 is H or when n is 1 R5 taken together with R3 comprises a double bond, n is 0 to 1, p is 0 to 2, m is 0 to 3; Ar1 and Ar2 are as disclosed in the Description; and are useful for treating hypertension or congestive heart failure and for preventing or treating restenosis following angioplasty; pharmaceutical compositions; and methods for production thereof. |