| abstract |
This patent describes 4-oxo-azetidine-2-sulphone acids and their salts with a general formula (I), where R1 means hydrogen, halogen, phenylacetamido group; R2 means hydrogen, halogen, phenylacetamido, phenoxyacetamido-, phtalimido-, 5-methyl-3-o- -chlorophenyl-isoxazol-4-carboxamido group; R3 means hydrogen, alkaline metal, alkaline earth metal, quarternary ammonium group, R4 means hydrogen, SO2O+NBu4-n, (CH3)2C=C-COOCH3, (CH3)2C=C- -COOCH2-phenyl group, (CH3)2C=C-COOCH2-C6H4-NO2-p, (CH3)2C=C- -COOCH2-C6H4-CH3-m. The compounds with a formula (I) can be applied as the intermediate products, when synthesis of beta lactam antibiotics is provided or as the components closed to antimicrobial preparations. |