| abstract |
The pharmaceutical composition consists of the pellets containing tetracycline compound and this compound is of the lowered capability, when talking about the release of the tetracycline compound in human stomach and of a higher capability, when talking about the release of the tetracycline compound in human casings, after oral application of the above mentioned pharmaceutical composition has been provided. These pellets contain the active quantity of 7- or 9-alkylamino-6- -deoxy-6-demethyltetracycline with 1 up to 6 carbon atoms in the alkyl residue or its additive salts with acids having no toxic effects, as the active compound with the antibacterial activity, mixed together with the active quantity of at least one excipient, suitable from pharmaceutical point of view, while the shape of them is related to a spherical bullet, the diameter of which is closed to the values 0,1 up to 2,5 mm, however the suitable diameter values are 0,8 up to 1,2 mm. |