| abstract |
Described are N-alkyl substituted pyrrolidin- benzoheterocyclic compounds of the general formula (I), wherein R1 is hydrogen, methyl, ethyl, propyl and allyl, R2 is halogen atom (F, Cl, Br, I), methoxy, nitro, cyano, amino and trifluoromethyl, Y is N or CH and Z is CH2, CH2CH2, CH=CH, O, S, SO, SO2 and NCH3 and their pharmaceutically acceptable salts; a method of preparation thereof and their use as inhibitors of biosynthesis of cholesterol and ergosterol. |