abstract |
Compounds of formula (I), wherein R' is hydrogen or alkyl; A is adamantyl or a mono-, bi- or tricyclic residue optionally unsaturated, a heterocyclic residue and/or substituted by hydroxy, alkanoyloxy, amino, aminoalkyl, halogen, alkyl, trialkylammoniumalkyl; (a) is a chain of 1 to 5 carbon atoms optionally containing a double bond or a NR'; R is hydrogen or phenyl; X is O or NR' or is absent; r and m are independently 0, 1 or 2; B is phenylene or cyclohexylene; Y is hydroxy or aminoalkyl optionally interrupted by an O; have anti-inflammatory and immunosuppressive activities. |