abstract |
The present application describes novel cyclic beta -amino acid derivatives of formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NR<a>, and S(O)p, and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease and as TNF- alpha inhibitors. |