http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SK-12752002-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dac022280ec96f54c694eb427655932 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 |
| filingDate | 2001-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dd2ce16fcac4548dfd35dfb2f67721b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba9695f185ed54d131f8bbad733c8435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c5388caea15f071e62760ce2e288814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ecc2fc35721d07e009c382a2d67427 |
| publicationDate | 2003-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SK-12752002-A3 |
| titleOfInvention | Substituted 3-phenyl-5-alkoxy-1,3,4-oxdiazol-2-ones, method of their preparation and their use as a medicament for inhibiting hormone-sensitive lipase |
| abstract | The invention relates to substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones of formula (I), wherein R<1> means substituted C1-C6-alkyl and C3-C9-cycloalkyl, R<2>, R<3>, R<4> and R<5> mean hydrogen, halogen, nitro, C1-C4-alkyl, C1-C9-alkyloxy, substituted C6-C10-aryl-C1-C4-alkyloxy, C6-C10-aryloxy, C6-C10-aryl, C3-C8-cycloalkyl or O-C3-C8-cycloalkyl or 2-oxo-pyrrolidin-1-yl, 2,5-dimethylpyrrol-1-yl or NR<6>-A-R-<7>, on the condition that R<2>, R<3>, R<4> and R<5> do not mean simultaneously mean hydrogen and at least one of the radicals R<2>, R<3>, R<4> or R<5> represents the radical 2-oxo-pyrrolidin-1-yl, 2,5-dimethylpyrrol-1-yl or NR<6>-A-R<7>, with R<6> = hydrogen, C1-C4-alkyl or substituted C6-C10-aryl-C1-C4-alkyl, A = a simple bond, COn, SOn or CONH, n = 1 or 2, R<7> = hydrogen, substituted C1-C18-alkyl,C2-C18-alkenyl, C6-C10-aryl-C1-C4-alkyl, C5-C8-cycloalkyl-C1-C4-alkyl, C5-C8-cycloalkyl, C6-C10-aryl-C2-C6-alkenyl, C6-C10-aryl, diphenyl, diphenyl-C1-C4-alkyl, indanyl or the group Het-(CH2)r-, with r = 0, 1,2 or 3 and Het = a saturated and unsaturated 5-7 membered heterocycle which can be benzoanellated and substituted. The invention also relates to a method for producing the same. The inventive compounds have an inhibitory effect on hormone-sensitive lipase, HSL. |
| priorityDate | 2000-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 258.