http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SK-115396-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C5-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-44 |
| filingDate | 1995-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed857442070bdda63aeb95d4b9c9c80f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f46baa9075c005fec3a0b34300e847d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a718c6f5123a9cfe356541b7f606032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da35b8def25746b32c3a01d834ba71cc |
| publicationDate | 1997-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SK-115396-A3 |
| titleOfInvention | Regiospecific processes to make cis-1-amino-2-alkanols |
| abstract | A regioselective process for synthesizing any enantiomer of cis-1-amino-2-indanol, or mixture of said enantiomers, from 1,2-indane diol, or 2-halo-1-indanol wherein the process comprises the steps of (a) mixing one equivalent of 1,2-indane diol in a solvent, said solvent selected from an alkyl nitrile or aryl nitrile; (b) adding to the mixture at least about 1,5 equivalents of an acid, said acid selected from a strong protic acid or a Lewis acid or an organic acid, and maintaining thereafter the temperature of the resulting mixture between about -70 DEG C and about 30 DEG C for a time period of between about 0.25 hours to about 6.0 hours; and (c) adding excess water to effect hydrolysis, and stirring for a time period of between about 0.5 hour and about 8.0 hours, at a temperature of between about 25 DEG C and about 80 DEG C, to give substantially cis-1-amino-2-indanol. |
| priorityDate | 1994-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.