http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SI-9820007-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ddb9f3656270bc5410be3679322fead |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
| filingDate | 1998-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c16123b3822661a07d1a127dd29a48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7a626548184cd593cd36d7da78bc158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a73726c157d976dcd5f2e2185982e70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9a15a08acd883d09c5da005b0e80663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c29b5055f758caa81388d952ffdf5c55 |
| publicationDate | 1999-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SI-9820007-A |
| titleOfInvention | A process for the preparation of a pharmacologically acceptable salt of N- (1 (S) -ethoxycarbonyl-3-phenylpropyl) -L-alanylamino acid |
| abstract | A process is provided for the preparation of a pharmacologically acceptable salt of N- (1 (S) -ethoxycarbonyl-3-phenylpropyl) -L-alanylamino acid, which comprises condensing amino acid and N- (1 (S) -ethoxycarbonyl-3-phenylpropyl) -alanine N-carboxyanhydride under a basic condition, the implementation of the decarboxylation conditioned between neutral and acid, to give N- (1 (S) -ethoxycarbonyl-3-phenylpropyl) -L-alanyl-amino acid and the formation of a pharmacologically acceptable salt thereof in which the production of the by-product (3) is prevented by carrying out a series of operations in an aqueous liquid to form a pharmacologically acceptable salt or to isolate a pharmacologically acceptable salt. The present invention allows the preparation of a pharmacologically acceptable salt of N- (1 (S) -ethoxycarbonyl-3-phenylpropyl) -L-alanyl-amino acids of high quality on a commercial scale, with high yield and economic efficiency. |
| priorityDate | 1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.