| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad3d51747a2eba1e7636894263252df4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate |
1997-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6d60ab0cf01b85d280c8aa7f93bdb17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_419aba9964301afd89a6cb0144f724eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7e0b06ddaaca9b5700247734e649ab2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b31ea1e903cc81083036268dea7d125 |
| publicationDate |
2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
SI-9700186-B |
| titleOfInvention |
A novel pharmaceutical form with controlled release of active substances |
| abstract |
A method of stabilizing active substances that are unstable in an acidic medium that is unstable during prolonged storage in the presence of water is sensitive to heating, using anhydrous granulation of active ingredients and dried pharmaceutically acceptable excipients for the production of pellet cores or granules. All pharmaceutically acceptable excipients used are dried before use so that their weight loss on drying is less than 1.0% of the total weight of the pharmaceutical excipient, preferably less than 0.5%. The organic solvents used in the anhydrous granulation process must contain less than 0.2% water. A new pharmaceutical formulation with controlled release of active substances which are unstable in acidic media, which are unstable during prolonged storage in the presence of water and at the same time sensitive to heating is also described. |
| priorityDate |
1997-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |