abstract |
A process for preparing compounds with ACE is describednby the inhibitory action of formula (I), wherein R vnclaim 1, as defined in the basic patentnreport no. P-9400290 (basic patent no.n9400290), wherein the carboxyl group is stereospecificnamino acids N- (1- (S) -ethoxycarbonyl-3-nphenylpropyl) -L-alanine is activated with thionyl chloridenat least one chlorine atom is replaced by a residuenheterocyclic ambivalent compounds, such as benzimidazole,n2-methylimidazole or triazole, into the intermediate,nand that it is part of a silylated amino acid by whichnmetabolize the resulting intermediate, in disilylatednand preferably 50% silylated amino acid inn50% in monosilylated form. |