abstract |
N-acyl-alpha-amino acid derivativesn0 R "R" 'nII \ /nL — c — N — c — C —Qnl IInR 'onI, in which L, R 'to R' 'and Q have the meaning givennin the description. They can be used to treat ornprophylaxis of adhesive binding disordersnproteins to the blood platelets, as well as the aggregation of bloodntile and cell-to-cell adhesion. Let's fix them withncleavage of protecting groups into appropriate protective groupsncompounds or by conversion of the cyano group to amidinengroup in the corresponding nitriles. |