| abstract |
Compounds of Formula:nA ---- (CH ;,) n-B-Qnwherein A, B, Q, Ri, R2, R2 ', X, Y, Z and n have in the claimn1 the meaning indicated, and, if necessary, in the form of enantiomers,nracemates, diastereomers or mixtures thereof,nor geometric isomers or mixtures thereof, and vnthe presence of a basic or acidic group thereofnacceptable salts, inhibit the enzyme camithine acyltransferasen1 (CAT-1) and are therefore useful in preventionndamage to ischemic tissue and therefore may be limitedninfarct size, improve heart function and preventnarrhythmias during and after myocardial infarction. Yes they donprepared by various methods which are inherentlynknown. |