| abstract |
The present invention is directed to a novel crystalline form of 6-hydroxy-3- (4- (2- (piperidin-1-yl) ethoxy) phenoxy) -2- (4-methoxy) benzo (b) thiophene hydrochloride and its use to the following fields: inhibition and prevention of estrogen-related disease states, including cardiovascular disease, hyperlipidemia and osteoroporosis, inhibition and prevention of other conditions such as endometriosis, uterine fibrosis, estrogen-dependent cancer (including breast and uterine cancer ), prostate cancer, benign prostatic hyperplasia, disorders of the central nervous system, including Alzheimer's disease, and prevention of breast cancer and increased ChAT activity.ŕ |