http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-183660-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8ae50a1ac4cd76423a4efc15db872d1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-249987 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-362 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-1871 |
| filingDate | 2008-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48be0dfa1f176d827520897b7ef21316 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c7f4b740b0236c210a0cb02644e299 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d258284618ee9826ea3961953818679 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b58379a65439c627a1145870117a737d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_333be0ddf437746e7c753df461427977 |
| publicationDate | 2012-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SG-183660-A1 |
| titleOfInvention | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
| abstract | MEDIA FOR MEMBRANE ION EXCHANGE CHROMATOGRAPHY BASED ON POLYMERIC PRIMARY AMINES, SORPTION DEVICE CONTAINING THAT MEDIA, AND CHROMATOGRAPHY SCHEME AND PURIFICATION METHOD USING THE SAMEMedia and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (such as Protein A or Protein G affinity column) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities in biological samples even at high conductivities and pH.Figure lA |
| priorityDate | 2007-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3782034 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419565472 |
Total number of triples: 23.