http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-172422-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 |
| filingDate | 2009-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db8e9032dacee4dcc4109af7ccb4dbd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d22fa02a0b9f50225db64a00953696b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80002c0443d1ff8721e67b4c6415394b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb891dbb6e00bae00bb5674989bc421a |
| publicationDate | 2011-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SG-172422-A1 |
| titleOfInvention | Derivatives of 2-pyridin-2-yl-pyrazol-3(2h)-one, preparation and therapeutic use thereof |
| abstract | 81 AbstractDERIVATIVES OF 2-PYRIDIN-2-YL-PYRAZOL-3(2H)-ONE, PREPARATION AND THERAPEUTIC USE THEREOFThe invention relates to compounds corresponding to formula (I), in the form of the base or of an acid-addition salt:(r)n„N,R,e,0 , 0 8 yin which n is equal to 0, 1, 2, 3 or 4; m is equal to 0, 1 or 2; o is equal to 0 or 1; X represents a group -CH2, —CH(R')-, -NH(R')- or a heteroatom chosen from 0 and S, it being understood that R' represents a group -(C1-05)alkyl, - (C1-05)alkoxy, -CH2-aryl, -C(0)R5 or -COOR5; R1 represents an oxo group, -COOR5, -W-OH or -W-NR5R6; R2 represents an H atom or a group chosen from the groups (i) -(C1-05)alkyl, (ii) -(C1-05)alkoxy, (iii) -COOR5, (iv) - NR5R6, (v) -C(0)-NR5R6, (vi) -S02-NR3R4, (vii) heteroaryl optionally substituted with a group -(C1-05)alkyl, (viii) —W-aryl, (ix) -W-heteroaryl, (x) - 0-W-aryl, (xi) -0-W-heteroaryl and (xii) -0-W-NR5R6; it being understood that R3 and R4, (i) which may be identical or different, represent, independently of each other, an H atom, a group -(C1-05)alkyl, -(C3- C6)cycloalkyl, aryl, heteroaryl, -CHrheteroaryl, -(C1-05)alkyl-NR5R6, -W-OH or -W-NR5R6; or (ii) form, together with the nitrogen atom that bears them, a heterocycloalkyl group optionally substituted with one or more groups chosen from the groups -(C1-05)alkyl and -CH2-aryl; W is a group -(C1- C5)alkylene, optionally substituted with one or more hydroxyl groups; R5 and R6, which may be identical or different, represent, independently of each other, a hydrogen atom or a group chosen from the groups -(C1-05)alkyl and the groups -(C3-C6)cycloallwl, and• also the process for preparing them and the therapeutic uses thereof. |
| priorityDate | 2008-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.