http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-11201908114U-A

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filingDate 2018-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e5fb8009be470ae143c2932218f51c4
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publicationDate 2019-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SG-11201908114U-A
titleOfInvention Pyrimidopyrimidinones useful as wee-1 kinase inhibitors
abstract INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 13 September 2018 (13.09.2018) WIP0 I PCT 0111111010 0111 °nolo Oil IIIII om mil 0111 OII 1111101 ois (10) International Publication Number WO 2018/162932 Al (51) International Patent Classification: CO7D 487/04 (2006.01) A61P 35/00 (2006.01) A61K 31/519 (2006.01) (21) International Application Number: PCT/GB2018/050620 (22) International Filing Date: 12 March 2018 (12.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1703881.1 10 March 2017 (10.03.2017) GB (71) Applicant: ALMAC DISCOVERY LIMITED [GB/GB]; Almac House, 20 Seagoe Industrial Estate, Craigavon BT63 5QD (GB). (72) Inventors: HEWITT, Peter; c/o Almac Discovery Limit- ed, Almac House, 20 Seagoe Industrial Estate, Craigavon BT63 5QD (GB). BURKAMP, Frank; c/o Almac Discov- ery Limited, Almac House, 20 Seagoe Industrial Estate, Craigavon BT63 5QD (GB). WILKINSON, Andrew; c/o Almac Discovery Limited, Almac House, 20 Seagoe Indus- trial Estate, Craigavon BT63 5QD (GB). MIEL, Hugues; c/o Almac Discovery Limited, Almac House, 20 Seagoe Industrial Estate, Craigavon BT63 5QD (GB). O'DOWD, Colin; c/o Almac Discovery Limited, Almac House, 20 Sea- goe Industrial Estate, Craigavon BT63 5QD (GB). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (74) Agent: BOULT WADE TENNANT; Verulam Gardens, 70 Gray's Inn Road, London WC1X 8BT (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 1-1 UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, • TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, - 00 (54) Title: PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS 1-1 0 (57) : The present invention relates to a compound that is useful as an inhibitor of the activity of Wee-1 kinase. The present \" invention also relates to pharmaceutical compositions comprising this compound and to methods of using this compound in the treatment 0 of cancer and methods of treating cancer.
priorityDate 2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 23.