http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-11201903462U-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5d3c1aa93ad7901a70e4f9249bae319 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M5-14228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2278 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2017-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75d34de56f201cafbec6c4da57517bdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e23f4eb67f51178dcc0b26056d9fe939 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51532280dba96db775898c34e3083a8e |
| publicationDate | 2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SG-11201903462U-A |
| titleOfInvention | Methods of delivering a neuroprotective polypeptide to the central nervous system |
| abstract | INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111111111 011101010111110111110101111111111111011111011111011111110111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\" WO 2018/075901 Al 26 April 2018 (26.04.2018) WIP0 I PCT (51) International Patent Classification: Transfer, 6011 Executive Blvd. Suite 325, Rockville, MD A61K 38/26 (2006.01) A61K 9/16 (2006.01) 20852 (US). A61K 47/34 (2017.01) A61P 25/28 (2006.01) (72) Inventors: KIM, Dong, Seok; 10000 Town Center (21) International Application Number: Ave., Apt. 413, Columbia, MD 21044 (US). KIM, Hee, PCT/US2017/057606 Kyung; 108-706, 501, Expo-ro, Yuseong-gu, Daejeon (22) International Filing Date: (KR). GREIG, Nigel, H.; 11 Anne Brent Garth, Phoenix, MD 21131 (US). 20 October 2017 (20.10.2017) (25) Filing Language: English (74) Agent: ZERHUSEN, Bryan, D. et al.; Locke Lord LLP, P.O. Box 55874, Boston, MA 02205 (US). (26) Publication Language: English (81) Designated States (unless otherwise indicated, for every (30) Priority Data: kind of national protection available): AE, AG, AL, AM, 62/410,748 20 October 2016 (20.10.2016) US AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (71) Applicants: PEPTRON, INC. [KR/KR]; 37-24, Yuseong- DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, daero, 1628 Beon-gil, Yuseong-gu, Daejeon, 305-811 (KR). HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, THE UNITED STATES OF AMERICA, as represented KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, by THE SECRETARY, DEPARTMENT OF HELATH MG, MK, MN, MW, MX, MY MZ, NA, NG, NI, NO, NZ, & HUMAN SERVICES [US/US]; Office of Technology Title: METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM (54) = FIG. 1A = b.0 3 = R ,. a a = Li c o I-) a 2 1 x ,,, W 0 I -,-- = _ = _ _= — = = - _ 0 7 14 21 Time (day) = : The present disclosure provides a method for delivering a neuroprotective polypeptide to at least a portion of a central (57) _ nervous system (CNS) of a subject. The method includes administering to the systemic blood circulation of the subject a therapeutically 1-1 , 1 effective amount of a neuroprotective polypeptide by a controlled-release formulation or a device providing a sustained release of the neuroprotective polypeptide including at least one neuroprotective polypeptide selected from the group consisting of GLP-1, exendin-4, 11 or a therapeutically effective GLP-1 or exendin-4 analogue; the neuroprotective polypeptide binds to and activates a receptor that binds at CT least one of GLP-1, exendin-4, or a combination thereof; and the controlled-release neuroprotective formulation or the sustained in release of the neuroprotective polypeptide enhances the delivery of the neuroprotective polypeptide across a blood-brain barrier (BBB) IN of the subject to at least a portion of the CNS relative to a rapid release formulation of the neuroprotective polypeptide. Also disclosed 0 --.... is Ot in 11 a method of treating a subject with a CNS-related disease or reducing at least one symptom of a CNS-related disease in a subject need thereof. 0 ei O [Continued on next page] WO 2018/075901 Al MIDEDIMOMOIDEIREEMOMMIMOIMMENVOIMIE OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — with sequence listing part of description (Rule 5.2(a)) |
| priorityDate | 2016-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.