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filingDate 2017-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c91db9dbd728477f20fe935198fb98a1
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publicationDate 2019-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SG-11201811345T-A
titleOfInvention Combination of ceftibuten and clavulanic acid for use in the treatment of bacterial infections
abstract INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1#11101111 0 11101 HOE 3E1 0 01111110111 OM 11101110110 11110 1111 OEN Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\"\"1 WO 2018/013870 Al 18 January 2018 (18.01.2018) WIP0 I PCT (51) International Patent Classification: JUBB, Adrian; c/o Achaogen, Inc., 1 Tower Place, Suite A61K 31/424 (2006.01) A61P 13/02 (2006.01) 300, South San Francisco, CA 94080 (US). ANDREWS, A61K 31/545 (2006.01) A61P 7/00 (2006.01) Logan; c/o Achaogen, Inc., 1 Tower Place, Suite 300, South A61K 45/06 (2006.01) A61P 17/02 (2006.01) San Francisco, CA 94080 (US). A61P 31/04 (2006.01) A61P 27/16 (2006.01) A61P 11/00 (2006.01) (74) Agent: POTTER, Karen et al.; Morrison & Foerster LLP, 12531 High Bluff Drive, Suite 100, San Diego, CA (21) International Application Number: 92130-2040 (US). PCT/US2017/042021 (81) Designated States (unless otherwise indicated, for every (22) International Filing Date: kind of national protection available): AE, AG, AL, AM, 13 July 2017 (13.07.2017) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (25) Filing Language: English DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (26) Publication Language: English HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (30) Priority Data: KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, 62/362,293 14 July 2016 (14.07.2016) US MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, 62/465,051 28 February 2017 (28.02.2017) US OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (71) Applicant: ACHAOGEN, INC. [US/US]; 1 Tower Place, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Suite 300, South San Francisco, CA 94080 (US). (84) Designated States (unless otherwise indicated, for every (72) Inventors: KRAUSE, Kevin, Michael; c/o Achaogen, kind of regional protection available): ARIPO (BW, GH, Inc., 1 Tower Place, Suite 300, South San Francisco, CA GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 94080 (US). CLOUTIER, Daniel, John; c/o Achaogen, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, Inc., 1 Tower Place, Suite 300, South San Francisco, CA TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 94080 (US). KOMIRENKO, Allison, Seiko; c/o Achao- EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, gen, Inc., 1 Tower Place, Suite 300, South San Francis- MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, co, CA 94080 (US). FRIEDLAND, Ian; c/o Achaogen, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, Inc., 1 Tower Place, Suite 300, South San Francisco, CA KM, ML, MR, NE, SN, TD, TG). 94080 (US). CIRZ, Ryan; c/o Achaogen, Inc., 1 Tower Place, Suite 300, South San Francisco, CA 94080 (US). Title: COMBINATION OF CEFTIBUTEN AND CLAVULANIC ACID FOR USE IN THE TREATMENT OF BACTERIAL = (54) INFECTIONS FIG. 4A PIXIE of AECOI='7S with ceftibuten 42 1,./ .): a d clavulanate (I peirti) \"4*- t no eta -tite. C115:CLA i oo atu A- CTS:CLA /CM , -÷ CTE:CLA i Cla 1-1 © IN GC M Il ----- (57) : Provided herein are combinations of (a) ceftibuten or a pharmaceutically acceptable salt thereof, or a hydrate of the GC 1-1 foregoing; and (b) clavulanic acid, or a pharmaceutically acceptable salt thereof for use in a method of treating or preventing a bacterial © infection. Also provided are pharmaceutical compositions, articles of manufacture, and kits comprising a) ceftibuten or a pharmaceu- el tically acceptable salt thereof, or a hydrate of the foregoing; and (b) clavulanic acid, or a pharmaceutically acceptable salt thereof, and ( ) 1.6 uses thereof. [Continued on next page] WO 2018/013870 Al MIDEDIMOMOIDEIRDERIONIEMIOMMOIMMEHOM Declarations under Rule 4.17: — as to the applicant's entitlement to claim the priority of he earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3))
priorityDate 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 44.