http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-11201809344Q-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87729a8c288798b59d4c537ff5edd381 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C47-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C47-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C47-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0fc9d9b76167492645dba5492167f8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a0ff04346c7e95f924fb15a06ca11dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff1cc9d0eb5076166dbdb405d2a963d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3203b63e1964192d2170ec2bda38f93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12c430c7bbea4f75034014b517fc9f8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c844ca7af0389f75603aafd364eaf84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3295af3fac63b1fbf9882134ba9a820b |
| publicationDate | 2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SG-11201809344Q-A |
| titleOfInvention | Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde |
| abstract | FIG12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 16 November 2017 (16.11.2017) WIPO I PCT omit VIII mum 0 VIII mil °nom mil (10) International Publication Number WO 2017/197083 Al C (51) International Patent Classification: A61K 31/44 (2006.01) C07D 401/04 (2006.01) C07D 231/02 (2006.01) (21) International Application Number: PCT/US2017/032104 (22) International Filing Date: 11 May 2017 (11.05.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/335,583 12 May 2016 (12.05.2016) US (71) Applicant: GLOBAL BLOOD THERAPEUTICS, INC. [US/US]; 400 East Jamie Court Suite 101, South San Fran- cisco, CA 94080 (US). (72) Inventors: LI, Zhe; c/o Global Blood Therapeutics, Inc., 400 E. Jaime Court Suite 101, South San Francisco, CA 94080 (US). GUZ, Nathan; c/o Global Blood Therapeutics, Inc., 400 E. Jaime Court Suite 101, South San Francisco, CA 94080 (US). SHAO, Yiyang; c/o Global Blood Therapeu- tics, Inc., 400 E. Jaime Court Suite 101, South San Francis- co, CA 94080 (US). COCUZ, Julieana; c/o Global Blood Therapeutics, Inc., 400 E. Jaime Court Suite 101, South San Francisco, CA 94080 (US). FRIESER, Markus; c/o Glob- al Blood Therapeutics, Inc., 400 E. Jaime Court Suite 101, South San Francisco, CA 94080 (US). YIANNIKOUROS, George, Petros; c/o Global Blood Therapeutics, Inc., 400 E. Jaime Court Suite 101, South San Francisco, CA 94080 (US). LIAO, Liang; c/o Global Blood Therapeutics, Inc., 400 E. Jaime Court Suite 101, South San Francisco, CA 94080 (US). (74) Agent: CLARK, Kevin et al.; Jones Day, 250 Vesey Street, New York, NY 10281-1047 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (54) Title: PROCESS FOR SYNTHESIZING 2-HYDROXY-6-((2-(1-ISOPROPYL-1H-PYRAZOL-5-YL)-PYRIDIN-3- YL)METHOXY)BENZALDEHYDE 1-1 00 O N 01 1-1 1 -1 (57) : Disclosed herein are processes for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H- pyrazol-5-y1)-pyridin-3- O yl)methoxy)benzaldehyde (also referred to herein as Compound (I)) and intermediates used in such processes. Compound (I) binds to \" hemoglobin and increases it oxygen affinity and hence can be useful for the treatment of diseases such as sickle cell disease. [Continued on next page] WO 2017/197083 Al MIDEDIMOMOIDEIROIDEMOMOIROBIRMODEVOIMIE SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) |
| priorityDate | 2016-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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