http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-11201809132R-A
Outgoing Links
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| filingDate | 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab39ea837cae521f113772d7787b9919 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0038e2de664e0ac3919b1baf036fc9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8a29cf65acd53f741afc15280f54880 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_678e0519933430302dc0f653da32cec9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_761c95e6252a2430fffb155a2559d9df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31af40f8bc00b2c66c296098ddf2f5a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d0a47e64e892c06e5fa7886ffff1ca6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1c2f70b687134a32d492ef17a02bf93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eddb55dc5ce8e6fcea723902e7dc3cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a62da28ff6396e50401f82b46d454af1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91cb0bf84dbe7dee04091d5b0d7aa9c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b2ea5411834b7213ed1fe03523cf8d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ada6aa8aa3b41d6967f8beadcd804f0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_365fc6fb04ddb7aed7031a298a75b8ee |
| publicationDate | 2018-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SG-11201809132R-A |
| titleOfInvention | Novel compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same |
| abstract | INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 11111111111111111111111111111111111111111111111111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/212534 Al 22 November 2018 (22.11.2018) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every CO7D 471/04 (2006.01) A61K 31/506 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K 31/437 (2006.01) CO7D 471/10 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (21) International Application Number: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, PCT/KR2018/005516 DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (22) International Filing Date: KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, 15 May 2018 (15.05.2018) MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (25) Filing Language: English SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, (26) Publication Language: English TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 10-2017-0060940 17 May 2017 (17.05.2017) KR kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (71) Applicant: LEGOCHEM BIOSCIENCES, INC. UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, [KR/KR]; (Munpyeongdong) 8-26, Munpyeongseo-ro, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Daedeok-gu, Daejeon 34302 (KR). EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, _ (72) Inventors: LEE, Dae Yon; (Munpyeongdong) MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, (KR). CHAE, Sang Eun; (Munpyeongdong) 8-26, KM, ML, MR, NE, SN, TD, TG). _ Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 (KR). JUNG, Eun Mi; (Munpyeongdong) 8-26, Munpyeongseo- Published: = ro, Daedeok-gu, Daejeon 34302 (KR). YANG, Eun Hye; — with international search report (Art. 21(3)) (Munpyeongdong) 8-26, Munpyeongseo-ro, Daedeok-gu, = — Daejeon 34302 (KR). CHOI, Yoon Jeong; (Munpyeong- — _ Bong) 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 (KR). CHUNG, Chul-Woong; (Munpyeong- dong) 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon = _ 34302 (KR). SHIN, Ju Hyun; (Munpyeongdong) 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 (KR). — KIM, Yun Ki; (Munpyeongdong) 8-26, Munpyeongseo- ro, Daedeok-gu, Daejeon 34302 (KR). KWON, Hyun Jin; = (Munpyeongdong) 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 (KR). RYU, Jeong Hee; (Munpyeong- = = = — Bong) 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 (KR). BAN, Eun Hye; (Munpyeongdong) 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 (KR). = KIM, Yong Zu; (Munpyeongdong) 8-26, Munpyeongseo- ro, Daedeok-gu, Daejeon 34302 (KR). OH, Yeong Soo; = (Munpyeongdong) 8-26, Munpyeongseo-ro, Daedeok-gu, = — Daejeon 34302 (KR). CHAE, Jeiwook; (Munpyeongdong) 8-26, Munpyeongseo-ro, Daedeok-gu, Daejeon 34302 = (KR). = Agent: CHOI, Eun Sun; 5F, Sungwon Tower, 28, Yeong- (74) dong-daero 85-gil, Gangnam-gu, Seoul 06180 (KR). - 1-1 7r M (54) Title: NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING In THE SAME ei 1-1 (57) : The present invention relates to novel compounds as autotoxin inhibitors for treatment and prophylaxis of conditions ei ---- or a disorder caused by autotaxin activation or increased concentration of lysophosphatidic acid, and also a pharmaceutical compo- GC sition containing the same. The novel compounds of the present invention are autotoxin inhibitors, and by inhibiting the production 1-1 © of lysophosphatidic acid, they are useful for treatment or prophylaxis of cardiovascular disorder, cancer, metabolic disorder, kidney f'1 disorder, liver disorder, inflammatory disorder, nervous system disorder, respiratory system disorder, fibrotic disease, ocular disorder, 0 cholestatic and other forms of chronic pruritus, or acute or chronic organ transplant rejection. |
| priorityDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 70.