http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-11201804789Q-A

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filingDate 2017-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86fd1ec27d9c3caa99a8b872c9fd3a59
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publicationDate 2018-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SG-11201804789Q-A
titleOfInvention Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
abstract FIG24124 M at. r.O.Vel waitie-tnen! paw se -V .ia, VetrinPak $811 , 3S1 (.4 , Noltrc(1) ¨ • cootounem 2 -6— Attraan basa! (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau 111111111111110 III OE III OE III II III IV IV 1111111111 IIIIIIIIIIIIIIIIIIIIIIIIIIII (10) International Publication Number WO 2017/118639 Al WIPO I PCT (43) International Publication Date 13 July 2017 (13.07.2017) Chef Lieu, 74270 Contamine-Sarzin (FR). QUATTRO- PANI, Anna; Rte de Cherie 2, 1207 GenOve (CH). POMEL, Vincent; 228, Chemin du Bois des Presses, 74570 Groisy (FR). LOUMAYE, Ernest; 29 Chemin de la Planta, 1223 Cologny (CH). POHL, Oliver; c/o ObsEva S.A., Chemin des Aulx 12, 1228 Plan-les-Ouates (CH). GOTTELAND, Jean-Pierre; 9 Rue Charles Humbert, 1205 Geneva (CH). (74) Agent: KATZAROV S.A.; 19 rue des Epinettes, 1227 GenOve (CH). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KIT, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (51) International Patent Classification: A61P 15/00 (2006.01) A61P 15/06 (2006.01) C07D 277/06 (2006.01) A61K 45/06 (2006.01) A61K 31/426 (2006.01) (21) International Application Number: PCT/EP2017/050099 (22) International Filing Date: 4 January 2017 (04.01.2017) English English (25) Filing Language: (26) Publication Language: (30) Priority Data: 14/987,586 4 January 2016 (04.01.2016) 62/274,674 4 January 2016 (04.01.2016) 62/395,664 16 September 2016 (16.09.2016) 62/407,918 13 October 2016 (13.10.2016) US US US US (71) Applicant: OBSEVA S.A. [CH/CH]; Chemin des Aulx 12, 1228 Plan-les-Ouates (CH). (72) Inventors: NAXOS PAGE, Patrick; Les Cyclades, Aven- ue de GenOve, 74160 Saint-Julien-en-Genevois (CH). SCHWARZ, Matthias; 43, Rue Philippe Plantamour, 1201 GenOve (CH). JORAND-LEBRUN, Catherine; (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, [Continued on next page] (54) Title: ALPHA-AMINO ESTERS OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF (57) : The invention provides phan laceutical com- positions comprising a compound of formula (I) or (II) and an additional therapeutic agent Also provided is the HCI salt and on crystalline form of the compound of formula (I). The com- pounds inhibit the prostaglandin F receptor (PGF2alpha) and thus useful in the treatment of disorders such as pretenn labor at the early gestational stage. OH (I) NH 2 W O 20 17 / 118639 Al WO 2017/118639 Al MIDEDIMOMOIDION0101113111101101100HOMEHOIS GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))
priorityDate 2016-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 34.