| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bab34457c0c62aadf06ac0280240a61 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4436
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-46 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate |
2012-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79b7c282ea3641e08226bba007aab35b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28fc75865ae2484ae6525c172a34a5cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ca7a4daa54d18e7ab3c1e67f4c6b181
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_128956a783c03244b828e90e7da9a5f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7bc2f88a512a88a77a06c21e0406e05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dde159214e6e45934af223320418a557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc1617cbcf6ccd4c683b08d023ea742e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45ad599971f34fd7692467e27057020d |
| publicationDate |
2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
SG-10201407430T-A |
| titleOfInvention |
N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate |
| abstract |
31 N-[5-(AMINOSULFONYL)-4-METHYL-l,3-THIAZOL-2-YL]-N-METHYL-2-[4-(2- PYRIDINYL)PHENYL]ACETAMIDE MESYLATE The present invention relates to an improved and shortened synthesis of N-[5- (aminosulfonyl)-4-methyl-l,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide and the mesylate monohydrate salt thereof by using boronic acid derivatives or borolane reagents while avoiding toxic organic tin compounds and to the mesylate monohydrate salt of N-[5-(aminosulfonyl)-4-methyl-l,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)- phenyl] acetamide which has demonstrated increased long term stability and release kinetics from pharmaceutical compositions. [No Figure] |
| priorityDate |
2011-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |