| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_847009a3413b72aba3a90b55df5153eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c68cbf64eb2686cb4c1ac0fbcd86804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6757cbc70ff786e3a5f9978e6ac504de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e979738ce8964199eb411b2ea841a2b3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 |
| filingDate |
1993-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bc312c96aad684f5ec5c9b08220d82e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fae34a78b4911ef13430e8b42491251
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02566a3b20a4ad22209bb0a8113fd824
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30b12a51e565703329c0c4a5637f9422 |
| publicationDate |
1994-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
SE-9301764-L |
| titleOfInvention |
Human calcium sensor |
| abstract |
The present invention relates to the isolation of a cDNA clone encoding the calcium sensor in human placenta and subsequent Northern blots confirming the mRNA expression also in human parathyroid and kidney tubule cells. Close sequence similarity is demonstrated with the rat Heymann nephritis antigen, a glycoprotein of the kidney tubule brush border with calcium binding ability. Immunohistochemistry substantiates a tissue distribution of the calcium sensor protein similar to that previously described for the Heymann antigen. It is propsed that the identified calcium sensor protein constitutes a universal sensor for recognition of variation in extracellular calcium, and that it plays a key role for calcium regulation via different organ systems. The calcium sensor protein belongs to the LDL-superfamily of glycoproteins, claimed to function primarily as protein receptors, but with functionally important calcium binding capacity. |
| priorityDate |
1993-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |