| abstract |
The new compounds of the general Formula I <IMAGE> (I) (wherein A stands for a C2-4 straight or branched chain alkylene group; R1 and R2 may be same or different and each stands for hydrogen, halogen, lower alkyl or lower alkoxy; or R1 and R2 together form a methylenedioxy group; R3 and R4 may be the same or different and each stands for C1=alkyl or C3 NOTEQUAL cycloalkyl or R3 and R4 together with the nitrogen atom, they are attached to, form a 4-7 membered ring which may contain as additional ring member an oxygen or sulfur atom or a further nitrogen atom and the latter nitrogen atom may optionally bear a C1-3 alkyl or benzyl substituent) and pharmaceutically acceptable acid addition salts and quaternary ammonium salts thereof possess valuable therapeutical properties and exert particularly useful transquillant-sedative, antidepressant, antiepileptic, antiparkinson, analgesic, local anaesthetic, gastric acid secretion inhibiting and/or antianginal effect. The new compounds of the general Formula I may be prepared by methods known per se. |