| abstract |
The disclosure relates to an apparatus for studying the bone formation or bone ingrowth in an implant in response to locally administered test substances of different types. The apparatus is of a bio-compatible material, preferably pure titanium, and is intented to be implanted in living bone tissue, primarily for animal experiment activities. The apparatus consists of an outer portion (2) with a central recess (2a) in which an inner portion (5) is inserted. The two portions (2, 5) form, in the assembled state, a bone formation through channel (9, 10) which is exposed when the inner portion (5) is removed, whereby examination of tissue (24) which has grown into the channel (9, 10) is made possible. The inner portion (5) further comprises a reservoir (13) for the substance whose bone formation promoting properties are to be tested. The reservoir (13) is connected to the bone formation channel (9, 10) by the intermediary of a capillary aperture (14), so-called diffusion capillary, for the supply of the contemplated test substance without simultaneous liquid flow. |