http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-8601826-D0
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bd6f1266ccbc7daaa0540e15838e56b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5549db88e6a0eb8d1db9b5693988bbeb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-545 |
filingDate | 1986-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d8815cee2bd5c1f97d3a9c9912a22be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d4e9a5fe23f1b55bd488a7d9edf5052 |
publicationDate | 1986-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | SE-8601826-D0 |
titleOfInvention | 5-PYRIMIDINECARBOXAMIDES AND TREATMENT OF LEUKEMIA AND TUMORS THEREWITH |
abstract | Novel 5-pyrimidinecarboxamides useful for regressing or inhibiting the growth of leukemia and tumors. The compounds have the formula: <IMAGE> wherein R1 is hydrogen or an alkoxy group having from one to four carbon atoms; R2 is hydrogen; alkyl, aryl, aralkyl, allyl, aralkenyl or aralkynyl, the alkyl, alkenyl or alkynyl moieties of which have from one to six carbon atoms, or a carbohydrate residue; R3 is hydrogen, C1-C4 alkyl or aryl; R4 is phenyl, naphthyl, benzyl, naphthylmethyl, thienyl, thienylmethyl or pyridyl; or phenyl, naphthyl, benzyl, naphthylmethyl, thienyl, thienylmethyl or pyridyl substituted with one or more of the following groups: hydroxy; halo; alkyl, alkoxy, alkylthio, haloalkyl or haloalkoxy having from one to four carbon atoms; carboxy; alkoxycarbonyl having from two to five carbon atoms; nitro; cyano; aryl; aryloxy; arylthio; benzyl; benzyloxy; naphthylmethyl; naphthylmethyloxy; thienyl; or thienylmethyl; and Y and Z are each independently oxygen, sulfur or selenium; and the pharmacologically acceptable addition salts thereof. |
priorityDate | 1985-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.