http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-8500462-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate | 1985-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbabcc4da78179fb20cc7bbcc742204d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_973f537e99b913f638c80c8094415f57 |
| publicationDate | 1985-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SE-8500462-L |
| titleOfInvention | SET TO MAKE PREDNISOLON DERIVATIVES AND INTERMEDIATES OF THIS PROCEDURE |
| abstract | A novel process for the preparation of prednisone derivatives of the formula <IMAGE> I wherein R1 is alkyl of 1 to 4 carbon atoms and R2 is selected from the group consisting of hydrogen and hydrocarbon of 1 to 8 carbon atoms comprising reacting a compound of the formula <IMAGE> II with a reducing agent to obtain a compound of the formula <IMAGE> III reacting the latter with a strong base in the presence of copper ions and oxygen to obtain a compound of the formula <IMAGE> IV reacting the latter with hydroxylamine to obtain a compound of the formula <IMAGE> V in its syn or anti isomeric form or a mixture thereof, reacting the latter with an acylating agent derived from a radical of the formula <IMAGE> and with a reducing agent to obtain a compound of the formula <IMAGE> VI in its Z or E isomeric form or a mixture thereof, subjecting the latter to treatment with an epoxidizing agent and then a dehydrating agent to obtain a compound of the formula <IMAGE> VII reacting the latter with a halogenation agent and subjecting the resulting product to hydrolysis to obtain a compound of the formula <IMAGE> VIII wherein Hal is a halogen and reacting the latter with a derivative of an acyl of the formula R1CO- to obtain the compound of formula I which are known compounds. |
| priorityDate | 1984-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.