| abstract |
Derivatives of 1,4-thiazane-3-carboxylic acid represented by the formula I, wherein R1 and R2 are hydrogen, an alkyl radical or a phenyl nucleus substituted or not or form a cycloalkyl radical; R3 is a hydroxyl group, OR9 group, wherein R9 may have different significations; R4 is hydrogen, alkyl or CONH2, R3 and R4 forming a hydantoin cycle, R5 and R6 representing hydrogen, alkyl, phenyl substituted or not; R7 is hydrogen, alkyl, particularly dimethyl, phenyl substituted or not, and the salts of those compounds. <IMAGE> as well as the pharmaceutical compositions containing them and the intermediaries for their preparation, having the formulas II, III, IV: <IMAGE>. |