http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-8204561-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_058e0be30e00d53858c67167df60aed5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 |
| filingDate | 1982-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cdf93ad6a0599d149cd0cfa51c87c5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e9aada645b2bf5ecc99882314f468a4 |
| publicationDate | 1983-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SE-8204561-L |
| titleOfInvention | SETTING TO TREAT PROLIFERATIVE SKIN DISEASES USING CERTAIN 6,8-SUBSTITUTED RIBOFURAN SYLPURIN-3, 5-CYCLIC PHOSPHATES |
| abstract | Proliferative skin diseases such as psoriasis are treated by topically administering cAMP analogs of the following formula to the afflicted skin site at a dose that preferentially and significantly activates type II protein kinase: <IMAGE> where: R6 is: (i) -NR1 R2 where R1 and R2 are independently selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, and cyclopentyl or are joined together with the nitrogen atom to form a hetrocyclic group having 4 to 5, inclusive, annular carbon atoms with the proviso that the total number of carbon atoms in the -NR1 R2 group is 4 or 5, or (ii) -XR where X is a chalcogen atom of atomic number 8 or 16 and R is alkyl of 4 or 5 carbon atoms, R8 is: (i) -X-(CH2)n R3 where X is defined previously, n is an integer in the range of 1 to 3, inclusive, R3 is hydrogen, alkyl of 1 to 7 carbon atoms, or phenyl substituted with 0 to 1, inclusive, nitro, halo of atomic number 9 to 35, inclusive, methoxy, hydroxy or methyl, or (ii) -NR4 R5 wherein R4 and R5 are independently selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, and phenalkyl of 7 to 9 carbon atoms with the provisos that only one of R4 and R5 may be hydrogen and the total number of carbon atoms in the -NR4 R5 group is in the range of 1 to 9, inclusive, and Z is hydrogen, an alkali metal cation or ammonium. |
| priorityDate | 1981-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.