abstract |
Process for chemically binding organic compounds containing carbohydrate residues, onto a support bearing at least one reactive -NH2, in which at least one -CH2OH group of the carbohydrate residue is transformed in a -CHO group, by oxidation and then the -CHO groups thus obtained are reacted with at least a reactive -NH2 carried by the side chains covalently bound on a solid, insoluble support, the side chains are chosen from among amines, polyamines, diacids, amino-acids, hydrazines, and are eventually coupled, by the intermediary of their reactive -NH2, with a nitrogen-containing compound chosen from aliphatic or aromatic amines, aliphatic or aromatic hydrazines, or amino acids, comprising eventually jointly a -SH group and a -NH2 group. Products resulting from this process and biological reagents containing said products as their active constituents. |