http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-8105902-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc133db407212aea34178c05dad8c6ad |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-133 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 |
| filingDate | 1981-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2024ea5065d980a4f397fb9bcb9a92a |
| publicationDate | 1983-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SE-8105902-L |
| titleOfInvention | PHARMACEUTICAL PREPARATIONS FOR TREATMENT OF GASTROHYPERACIDITY, GASTRIT AND GASTRODUODENAL ULCERA |
| abstract | Compsn. contains as active ingredients alginic acid (I) and tris(hydroxymethyl) aminomethane (II) at wt. ratio 1:0.7-2, and a 5 wt.-vol.% aq. soln. of the compsn. has pH 6-9. Pref. formulations are tablets, powders or aq. solns. of concn. 3-10%, partic. with wt. ratio (I):(II) of 1:1.2 and pH 8.5-8.7. The compsns. are useful for treating gastric hyperacidity, gastritis and gastro-duodenal ulcers. They not only neutralise excess acid but also protect the wall of the stomach (by forming a hydrophilic gel). The usual dose is 10-200 mg per kg per day and the compsns. cause no toxic manifestations in mice, rats or rabbits at 1.5g per kg (orally) nor in rabbits at 0.5 g kg intraperitoneally. A typical powder formulation was made by blending 1 kg of food-grade (I) with 0.7-2 kg (II). This could be compressed into 250 mg tablets or made up into 500 mg sachets (for dissolution in 50-100 cc water). |
| priorityDate | 1981-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.