http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-8004868-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9433d383d1922b3df0ca6c182c7d3925 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C239-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 |
| filingDate | 1980-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16867a61eb0d75c5ec3c60ab63854c5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67c66a114b51c8632605cfdabc6c50f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17fff87de2f2916d7adf3df537816d24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4620ed9514589e3eb827201367898dcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f7b4d992b7e80e57f1b6d6bba9a083c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_158a8c2c8e310dcd96888055c7ea14f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1295d65213919c9b268f4f2d4e5312d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_611a5a103ffe76f083d62f7ee76d7829 |
| publicationDate | 1981-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SE-8004868-L |
| titleOfInvention | NEW OXIMETERS, PREPARATION OF THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH ETHERS |
| abstract | The invention relates to novel oxime ethers of the general formula /I/ and acid addition salts and quaternary ammonium derivatives thereof, <IMAGE> /I/ wherein A represents a C2-6 straight or branched alkylene chain, R and R1 each represent a C1-6 alkyl group or they form together with the adjacent nitrogen atom a heterocyclic ring containing 4 to 7 carbon atoms and optionally a further hetero atom, i.e. an oxygen, sulfur or nitrogen atom, and said ring may be optionally substituted by a C1-3 alkyl, phenyl or benzyl group, R2 and R3 each denote a hydrogen atom or together form a valency bond, R4 denotes a C1-10 alkyl or C2-10 alkenyl group, and n denotes an integer from 3 to 7. The compounds of the general formula /I/ are prepared according to the invention by reacting a cycloalkane derivative of the general formula /II/ <IMAGE> /II/ wherein R2, R3, R4 and n have the same meaning as above, whereas Y denotes an oxygen or sulphur atom or a =N-OH group with an aminoalkyl derivative of the general formula /III/ <IMAGE> /III/ wherein R, R1 and A have the same meaning as stated above and Z means a halogen atom or a H2N-O- group or a salt thereof in the presence of a basic condensing agent. The new compounds of the general formula /I/ possess valuable nicotine-lethality inhibiting, local anaesthetic, analgesic effects, which are, in case of certain compounds, complemented by anti-hypertensive, maximum electroshock and tetracorspasm inhibiting, ulcus inhibiting and motility inhibiting effects, and can be applied to advantage in the therapy. |
| priorityDate | 1979-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.