http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-8003507-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-472 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-02 |
| filingDate | 1980-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c6a22fe9d97e189c2ffdac66cc01186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b3c80fc1fcba30fedf56ce5159fb1c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3350080c0e8b922be60a05bc7b05e344 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_558be4e01b415175ae221fec7db28f32 |
| publicationDate | 1980-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SE-8003507-L |
| titleOfInvention | SET TO MAKE A TETRAHYDROISOKINOL COMPOUND |
| abstract | 1-(3,4,5-trimethoxybenzyl)-5,7-dihydroxy-1;2,3,4-tetra-hydroisoquinoline (I) can be prepared by the step(s) of: (A) subjecting a N-¢.alpha.-(3,4,5-trimethoxybenzyl)-3,5-dibenzyloxy-benzyl!aminoacetaldehyde dialkylacetal (II) to catalytic hydrogenation under acidic conditions, or (B) (i) treating a N-benzyloxycarbonyl-N-¢.alpha.-(3,4,5-trimethoxy-benzyl)-3,5-dibenzyloxybenzyl!-aminoacetaldehyde dialkylacetal (III) with an acid to give 1-(3,4,5-trimethoxybenzyl)-2-benzyloxycarbonyl-5,7-dibenzyloxy-1,2-dihydroisoquinoline (IV), and then (ii)subjecting the compound (IV) to catalytic hydrogenation, or (C) (i) subjecting a N-formyl-N-¢.alpha.-(3,4,5-trimethoxyvenzyl)-3,5-dibenzyloxy (or dihydroxy)-benzyl!-aminoacetaldehyde dialkylacetal (V) to catalytic hydrogenation under acidic conditions to give 1-(3,4,5 trimethoxybenzyl)-2-formyl-5,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (VI), or treating the compound (V) with an acid to give 1-(3,4,5-trimethoxybenzyl)-2-formyl-5,7-dibenzyloxy (or dihydroxy)-1,2-dihydroisoquinoline (VII) and subjecting the compound (VII) to catalytic hydrogenation to give the compound (VI), and then (ii)subjecting the compound (VI) to deformylation. |
| priorityDate | 1979-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.