| abstract |
Novel beta -lactones of 2-hydroxy-cyclopentane-carboxylic acids of the formula <IMAGE> I wherein R1 is selected from the group consisting of hydrogen and methyl and R2 is selected from the group consisting of -CH2-O-CH2-CH3 and -X-Ar, X is selected from the group consisting of -O- and -CH2-, Ar is an optionally substituted member selected from the group consisting of thienyl, thiazolyl, phenyl and thiadiazolyl, the optional substituents being at least one member selected from the group consisting of halogen and -CF3 and thw wavy lines indicate that the groups may be in the alpha , beta or beta , alpha -positions or mixtures thereof having hypotensive activity and their preparation. |