| abstract |
Novel thiocarbamide derivatives of the formula <IMAGE> in which the substituents R1, R2, R3, R4, R5 and R6 have the meaning given in each case in Patent Claim 1, are obtained by reacting an isothiocyanate of the formula <IMAGE> the corresponding dithiocarbamic acid of the formula <IMAGE> its esters or acid halide with an amine of the formula R4NHR5 in the melt or in an inert solvent. The reaction products have favourable diuretic, saluretic, analgesic and/or antidepressive action even at a low dose, combined with low toxicity. |