http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-7409946-L
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d629f98a51b15993f56f9e04fdea237f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 |
filingDate | 1974-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7684883c8fdc1c391ef159d2f1c2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1281d0aeed989232114614f898645b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51123c99c79d83c37d3a0d680cc1c55f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e0b85c902d0fabe9678f17069aaac9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23acdf4c68c7ee82af251bfb099e1bdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9472e36e1ab8bfad1f92cf098e4f24f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cbe6a842478df968c06122cbdd6e036 |
publicationDate | 1975-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | SE-7409946-L |
abstract | 1473733 Pseudo trisaccharides SCHERICO Ltd 1 Aug 1974 [6 Aug 1973 19 March 1974 (2)] 33968/74 Heading C2C The invention comprises 1-N substituted derivatives of the 4,5-di-(aminoglycosyl)-1,3- diaminocyclitols gentamicin A, gentamicin B, gentamicin B 1 , gentamicin C 1 , gentamicin C 1a , gentamicin C 2 , gentamicin C 2a , gentamicin C 2b , gentamicin X 2 , sisomicin, vendamicin, tobramycin, Antibiotic G-418, Antibiotic 66-40B, Antibiotic 66-40D, Antibiotic J1-20A, Antibiotic J1-20B, Antibiotic G-52, mutamicin 1, mutamicin 2, mutamicin 4, mutamicin 5 and mutamicin 6, where the substituent is -CH 2 X with X being hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, hydroxyalkyl, aminoalkyl, N-alkylaminoalkyl, aminohydroxyalkyl, N-alkylaminohydroxyalkyl, phenyl, benzyl or tolyl, said aliphatic radicals having up to seven carbon atoms and, if substituted by amino and hydroxy, bearing the substituents on different C atoms and pharmaceutically acceptable acid addition salts thereof. The compounds of the invention may be prepared by treating one of the above named 4,6-di-(aminoglycosyl)-1,3- diaminocyclitols which may have aminoprotecting groups at any position other than position 1, with an aldehyde of formula X<SP>1</SP>-CHO, with X<SP>1</SP> being a group as defined for X above wherein any amino or hydroxy group present may be protected in the presence of a hydride donor and reducing agent and, if required, removing all protecting groups present in the molecule the last process step being followed by isolating the derivative as such or as a pharmaceutically acceptable acid addition salt. |
priorityDate | 1973-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.