http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-0203551-D0

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_379a600b6d7f336a460fafea157cec22
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64
filingDate 2002-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc1a4ec1c297fad7098afede922ba44f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a2748c8ce74e9679aec630880f35876
publicationDate 2002-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SE-0203551-D0
titleOfInvention Prothrombin purification
abstract One aspect of the invention relates to a process for the preparation of a purified solution of prothrombin and factor X from a fraction of blood plasma obtainable by cryoprecipitation, which process comprises subjecting such a fraction to prepurification steps and to the following steps: (a) metal chelate gel chromatography and (b) affinity gel chromatography. Another aspect of the invention relates to a solution of prothrombin and factor X, wherein the prothrombin has the ability of being activated to thrombin in the substantial absence of other enzymes or cofactors. A further aspect of the invention relates to the use of a solution of prothrombin and factor X for the preparation of a thrombin solution.
priorityDate 2002-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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