Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e169ee72c889f4021b92a53c9c71ec3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7cfefe819a15e3c4013b8047fb8f997 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22c93235b098e62d65596da3b29c757d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-64 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate |
2001-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_546e0d47c488b63c0d27f46b661d33b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f1aad17307fc7b53a6d6155b6116f6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1423ce4b496e07c4b5e9ab78b09907b3 |
publicationDate |
2001-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
SE-0102627-D0 |
titleOfInvention |
Methylation resistant vectors |
abstract |
The invention relates to vectors produced in a donor host cell, which upon transfer into a receiver host cell maintain the desired expression of the nucleotide sequences which are located within the vector. The maintenance of the desired expression is achieved due to that the vector at least partly remains unmethylated within the receiver host cell. The donor host cell being different as compared to the receiver host cell and the receiver host cell being capable of methylating DNA. To prevent methylation, cytosines in a CpG motif in the nucleotide sequence to be transferred are replaced with cytosine analogues resistant to methylation. The invention also relates to methods for the production of such vectors and the use of the vectors in industry as well as in medicine. |
priorityDate |
2001-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |